Method of separating isomers of a crown ether compound to recover cis-syn-cis isomer from dicyclohexyl 18-crown 6.
US5082955A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 11, 1990 |
| Grant date | Jan 21, 1992 |
| Priority date | — |
| Expiry date | Dec 11, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D323/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A method for separating the isomers of a crown ether compound and making it possible to recover in particular the pure cis-syn-cis isomer from DCH 18C6 includes: PA0 a) dissolving in an organic solvent a mixture of the isomers of said crown compound including the cis-anti-cis isomer and the cis-syn-cis isomer, PA0 b) adding uranyl nitrate to the solution obtained in stage a) in sufficient quantities so that virtually all of the isomers, except the cis-syn-cis isomer, are precipitated in the form of complexes with the uranyl nitrate, PA0 c) separating the formed precipitate, PA0 d) recovering the cis-syn-cis isomer from the solution, and PA0 e) recovering the cis-anti-cis isomer from the precipitate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.