Composition of M-CSF conjugated to cytotoxic agents and a method for treating cancers characterized by over-expression of the c-fms proto-oncogene
US5084556A · kind A · utility
10Cited by
4References
5Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jun 28, 1990 |
| Grant date | Jan 28, 1992 |
| Priority date | — |
| Expiry date | Jun 28, 2010 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/6425
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A composition and method for treating cancers characterized by over-expression of the c-fms proto-oncogene/M-CSF receptor protein are provided. The composition involves a M-CSF polypeptide cross-linked to a cytotoxic agent capable of crossing into the cytoplasm of the cell bearing the receptor and killing the cell.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.