Integrated temperature control/alignment system for high performance capillary electrophoretic apparatus
US5085757A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 28, 1989 |
| Grant date | Feb 4, 1992 |
| Priority date | — |
| Expiry date | Aug 28, 2009 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2021/0389
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
An integrated temperature control/alignment system for use with a high performance capillary electrophoretic apparatus comprises a complementary pair of capillary column mounting plates formed from an electrically insulative, high thermal conductivity material for mounting a capillary column. The first mounting plate includes a well having a predetermined circumference, first and second grooves contiguous with the well and ports formed in the grooves and extending through the plate. The second mounting plate includes a plug configured for insertion in the well and ports aligned with the ports of the first mounting plate. Respective ends of the capillary column are seated and locked in the grooves to preposition the capillary column with respect to the ports. Capillary columns of varying lengths may be mounted within the mounting plates by coiling the intermediate portion thereof within the well to increase or decrease the working length of the column in predetermined increments, depending upon the particular application. Optical coupling elements are disposed in the ports to couple sampling and reference radiation to and from the mounted capillary column. The temperature of substan…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.