Immunoseparating strip
US5085988A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Jul 5, 1990 |
| Grant date | Feb 4, 1992 |
| Priority date | — |
| Expiry date | Jul 5, 2010 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/816
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method and device for determining the presence of an analyte in a sample suspected of containing the analyte are disclosed. The method involves contracting a test solution containing the sample, an antibody for the analyte, and a conjugate of the analyte and a label with a contact portion of a strip of bibulous material capable of being traversed by the test solution through capillary action. The strip contains a first receptor capable of binding to the conjugate. The first receptor is non-diffusively bound to a situs on the strip separate from the contact portion of the strip. The strip further contains a second receptor capable of binding the antibody to the analyte between the situs and the contact portion. The second receptor is non-diffusively bound to the strip. At least a portion of the test solution is allowed to traverse the strip by capillary action and thereby contact the situs. The strip is exposed to a signal producing means capable of interacting with the label to produce a signal in relation to the amount of analyte in the test solution. The signal produced at the situs is then detected.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.