Microbial transformation process for antihypertensive products
US5085992A · kind A · utility
20Cited by
3References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 25, 1991 |
| Grant date | Feb 4, 1992 |
| Priority date | — |
| Expiry date | Feb 25, 2011 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/886
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Fermentation of the microorganism Streptomyces sp. MA6751 (ATCC No. 55043) in the presence of the Angiotensin II (A II) receptor antagonist ##STR1## yields an N2-tetrazole .beta.-glucuronide analog which is also an A II antagonist useful in the treatment of hypertension and congestive heart failure and other indications known to respond to A II antagonists.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.