Patent · US Expired

Method of microencapsulation of hyperbaric gas

US5086620A · kind A · utility

73Cited by
7References
38Claims
0Family size

Assignee

Inventor

Key dates

Filing dateFeb 14, 1991
Grant dateFeb 11, 1992
Priority date
Expiry dateFeb 14, 2011

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61M2202/0476
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Method of encapsulating a hyperbaric gas for the treatment of diseases in humans with encapsulated gaseous precursors, such as microbubbles of oxygen. The method includes the step of immersing a receptacle containing an encapsulating material into a reaction vessel. An ultrasonic probe is then inserted into the reaction vessel. When the vessel is sealed, a source of hyperbaric gas is communicated therewith, and the vessel is then immersed within a cooling fluid so that the hyperbaric gas condenses. Thermal energy is then applied to the receptacle and ultrasound energy is delivered to the ultrasonic probe. When the probe vibrates, hyperbaric gas is distributed within the heated encapsulating material. After the cooling fluid chills the mixture of hyperbaric gas in the encapsulating material, the hyperbaric gas is entrapped therewithin. The encapsulated oxygen precursor can be used to treat atherosclerosis, infections and neoplasms, as well as to provide systemic oxygenation of tissues.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.