Patent · US Expired

Catheter and method for locally applying medication to the wall of a blood vessel or other body lumen

US5087244A · kind A · utility

473Cited by
15References
21Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 27, 1990
Grant dateFeb 11, 1992
Priority date
Expiry dateSep 27, 2010

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61M2025/105
  • WIPO fieldMedical technology
  • WIPO sectorInstruments

Abstract

A method and catheter for use in practicing the method are provided by which a highly concentrated medication or chemotherapeutic agent can be applied locally under sufficient pressure to cause the medication or agent to penetrate into the localized tissue. The total volume of medication or agent is quite small, well below levels that might cause an adverse reaction in other parts of the body. The catheter includes a thin walled flexible balloon having a plurality of minute holes through which medication may flow at a low flow rate. The balloon is inflated with the medication under pressure and the flow rate of the order of a few ccs per minute is controlled by the minute holes in the balloon. In practicing the method of the invention, the balloon is selected such that its inflated diameter will correspond to or be slightly greater than the diameter of the lumen into which it is to be placed so that when the balloon is inflated, it will contact intimately the surface of the lumen. Inflation of the balloon with the medication will cause a thin film to spread between the balloon and the lumen, the film being maintained under a sufficient pressure to penetrate significantly the surrou…

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.