Patent · US Expired

Hollow granular medicine and its preparation

US5087455A · kind A · utility

8Cited by
11References
39Claims
0Family size

Assignees

Inventors

Key dates

Filing dateSep 20, 1990
Grant dateFeb 11, 1992
Priority date
Expiry dateSep 20, 2010

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K9/1676
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A granular medicine with slow drug-release characteristics that is sufficiently absorbed in the intestines, in which the granular medicine has a hollow spherical structure, a drug is dispersed in the shell, which mainly consists of an enteron-soluble polymer. The method for preparing the medicine includes the steps of: (a) mixing a hydrophilic or hydrophobic drug with an enteron-soluble polymer in a mixture of an aliphatic alcohol and a chlorohydrocarbon; and (b) pouring this mixture into water or an aqueous medium, and stirring the solution to precipitate the medicine.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.