Hollow granular medicine and its preparation
US5087455A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | Sep 20, 1990 |
| Grant date | Feb 11, 1992 |
| Priority date | — |
| Expiry date | Sep 20, 2010 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/1676
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A granular medicine with slow drug-release characteristics that is sufficiently absorbed in the intestines, in which the granular medicine has a hollow spherical structure, a drug is dispersed in the shell, which mainly consists of an enteron-soluble polymer. The method for preparing the medicine includes the steps of: (a) mixing a hydrophilic or hydrophobic drug with an enteron-soluble polymer in a mixture of an aliphatic alcohol and a chlorohydrocarbon; and (b) pouring this mixture into water or an aqueous medium, and stirring the solution to precipitate the medicine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.