Gradient generation control for large scale liquid chromatography
US5089124A · kind A · utility
30Cited by
6References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 18, 1990 |
| Grant date | Feb 18, 1992 |
| Priority date | — |
| Expiry date | Jul 18, 2010 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01D15/166
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
Precise gradient control is accomplished using a high flow three-way valve, appropriate mixing, and precise metering control. Gradient elution profiles are generated for flow rates above 100 ml/min. Control involves precise selection of two solvents, and correction factors for valve lag times and pump/valve synchronizations. The gradient is controlled simultaneously with other non-timed operations through a single microprocessor controller.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.