Pre-storage filtration of platelets
US5089146A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 12, 1990 |
| Grant date | Feb 18, 1992 |
| Priority date | — |
| Expiry date | Feb 12, 2010 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M2202/0439
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Filtration of white blood cells (WBCs) directly from platelet rich plasma (PRP) rather than from subsequently made platelet concentrates (PC). Earlier filtration is effective at removing most WBCs with minimal platelet loss and permits storage of platelets for at least 5 days. The filtration is preferably done with a closed, ready-to-use system comprising a WBC filter disposed between a first blood bag and at least two empty secondary bags. A fourth bag may be included in the closed system to contain a platelet additive solution. System can remove at least 95% of the WBCs with less than 10% loss in platelets. In very preferred embodiments at least 99.5% of the original WBCs are removed by filtration prior to platelet storage.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.