Process for the preparation of optically active 2-arylpropionic acids and pharmaceutical compositions containing the same
US5089405A · kind A · utility
10Cited by
3References
9Claims
0Family size
Assignee
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Key dates
| Filing date | Jul 26, 1989 |
| Grant date | Feb 18, 1992 |
| Priority date | — |
| Expiry date | Jul 26, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P7/40
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
S Enantiomers of 2-arylpropionic acids are made by enantioselective hydrolysis of the corresponding racemic 2-arylpropionamides in the presence of a microorganism, or of an enzyme derived therefrom, able selectively to hydrolyze racemic .alpha.-phenylpropionamide to S .alpha.-phenylpropionic acid. The S Enantiomers obtained may be incorporated into antiinflammatory, analgesic and antipyretic compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.