Pharmaceuticals and dietetics containing acylamino acid derivatives

US5089492A · kind A · utility

Assignees

• Kali-Chemie Aktiengesellschaft · DE
• Pfrimmer Kabi GmbH & Co. KG · DE

Inventors

• Klaus-Guenter Gerling · Laatzen, DE
• Henning Heinemanmn · Lehrte, DE
• Andreas Meier · Wilhermsdorf, DE
• Klaus Langer · Erlangen, DE

Key dates

• Filing date: May 24, 1990
• Grant date: Feb 18, 1992
• Expiry date: May 24, 2010

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D317/32
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Acylamino carboxylic acid derivatives corresponding to the formula I ##STR1## in which the groups R.sup.1, R.sup.2, R.sup.3, Z.sup.1 and Z.sup.2 represent functional groups specified in the claims. The acylamino carboxylic acid derivatives have valuable pharmacological properties which, in particular, favorably influence nitrogen metabolism. The compounds are useful as active ingredients in pharmaceutical and/or dietetic compositions for treatment or prevention of nitrogen metabolism disturbances in large mammals caused, for example, by liver or kidney damage.