Substituted 4-aminoquinoline derivatives as gastric acid secretion inhibitors
US5089504A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 23, 1989 |
| Grant date | Feb 18, 1992 |
| Priority date | — |
| Expiry date | Feb 23, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D215/42
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Substituted 4-aminoquinazoline derivatives of the formula: ##STR1## in which R.sup.1 is hydrogen, C.sub.1-6 alkyl, C.sub.1-6 alkoxy, C.sub.1-6 alkoxyC.sub.1-6 alkyl, C.sub.3-6 cycloalkyl, C.sub.3-6 cycloalkylC.sub.1-6 alkyl, phenylC.sub.1-6 alkyl, the phenyl group being optionally substituted; PA0 R.sup.2 is hydrogen, C.sub.1-6 alkyl, C.sub.1-6 alkoxy, amino, C.sub.1-6 alkylthio, halogen, cyano, hydroxy, carbamoyl, carboxy, C.sub.1-6 alkanoyl or trifluoromethyl; PA0 m is 1 to 3; PA0 p is 0 to 4; PA0 R.sup.3 is COR.sup.4 ; PA0 R.sup.4 is hydroxy, C.sub.1-6 alkoxy, or NR.sup.5 R.sup.6 ; PA0 R.sup.5 and R.sup.6 are each hydrogen or C.sub.1-6 alkyl or together with the nitrogen atom to which they are attached form a heterocyclic ring; and PA0 R.sup.7 is hydrogen, C.sub.1-6 alkoxy or C.sub.1-6 alkyl; PA0 or a salt thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.