Selective 6-acylation of sucrose mediated by cyclic adducts of dialkyltin oxides and diols
US5089608A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 23, 1990 |
| Grant date | Feb 18, 1992 |
| Priority date | — |
| Expiry date | Mar 23, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H23/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
There is disclosed a process which comprises the steps of: PA1 (a) reacting a di(hydrocarbyl)tin oxide such as a dialkyltin oxide with a dihydric alcohol, alkanolamine, or an enolizable .alpha.-hydroxyketone in an inert organic reaction vehicle, with removal of water, at a temperature and for a period of time sufficient to produce a cyclic adduct of said dialkyltin oxide and said dihydric alcohol, alkanolamine, or enolizable .alpha.-hydroxyketone; PA1 (b) reacting said cyclic adduct product of Step (a) with sucrose in an inert organic reaction vehicle such as a dipolar aprotic liquid, at a temperature and for a period of time sufficient to produce a 6-O-[dihydrocarbyl(hydroxy- or amino- or oxohydrocarbyl)stannoxyl]sucrose; and PA1 (c) reacting the product of Step (b) with an acylating agent to produce a sucrose-6-ester.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.