Patent · US Expired

Process for the enzymatic dispersal of Mycobacterium bovis - BCG

US5091308A · kind A · utility

6Cited by

4References

9Claims

0Family size

Assignee

The Board of Trustees of the University of Illinois · US

Inventors

Melvin E. Klegerman · Chicago, US
Michael Groves · Gevelsberg, DE

Key dates

Filing date	Jan 29, 1990
Grant date	Feb 25, 1992
Priority date	—
Expiry date	Jan 29, 2010

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P31/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Mycobacterium bovis BCG suspensions are treated with a protease enzyme such as pronase, resulting in the production of suspensions having smaller aggregates and single cells. Such suspensions, when processed into vaccines, exhibit improved immunizing potential against cancer and would be expected to exhibit improved immunizing potential against tuberculosis.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.