Preparation of immunologically active cell wall components from archaebacteria

US5091364A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Jorg Baumgarten · Wuppertal, DE
• Helmut Brunner · Wuppertal, DE
• Inge E A Flesch · Belconnen, AU
• Heinz Hildebrand · West Haven, US
• Norbert Piel · Erkrath, DE
• Michael Sperzel · Wuppertal, DE

Key dates

• Filing date: Jul 25, 1990
• Grant date: Feb 25, 1992
• Expiry date: Jul 25, 2010

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S530/82
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A process for the preparation of glycoproteins and proteins from cultures of archaebacteria, comprising culturing archaebacteria, isolating glycoprotein and/or protein from the archaebacteria or their cell walls, enzymatically degrading the glycoprotein and/or protein, purifying and isolating the degradation products, and separating those fractions in the individual purification steps based on the biological activity of the fraction. The products increase the body's defenses against infection.