Immunostimulating guanosine derivatives and their pharmaceutical compositions
US5093318A · kind A · utility
30Cited by
2References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 5, 1988 |
| Grant date | Mar 3, 1992 |
| Priority date | — |
| Expiry date | May 5, 2008 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/55511
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
7,8-Disubstituted guanosine nucleoside derivatives are found to be potent immune response enhancing agents in human and animal cells. 7-Substituents are heteroatom-substituted-hydrocarbyl radicals having a length greater than ethyl and less than about decyl. 8-Substituents are .dbd.O, .dbd.S, .dbd.Se and .dbd.NCN. Compositions and methods of use are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.