Substituted phenylsulphonamides

US5093340A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Klaus-Helmut Mohrs · Wuppertal, DE
• Elisabeth Perzborn · Wuppertal, DE
• Friedel Seuter
• Romanis Fruchtmann · Cologne, DE
• Christian Kohlsdorfer · Lechenich, DE

Key dates

• Filing date: Sep 24, 1990
• Grant date: Mar 3, 1992
• Expiry date: Sep 24, 2010

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D215/26
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

New phenylsulphonamides of the formula in which ##STR1## R.sup.1 represents a pyridyl, quinolyl or isoquinolyl radical which is unsubstituted or substituted by halogen, alkyl, cycloalkyl, alkoxy, cyano, nitro, halogenoalkyl, halogenoalkoxy, alkoxycarbonyl or alkylsulphonyl, PA1 R.sup.2 represents hydrogen, cyano, nitro, halogen, alkyl, alkoxy, halogenoalkyl, halogenoalkoxy or alkoxycarbonyl, PA1 R.sup.3 represents an aryl radical which is unsubstituted or monosubstituted, disubstituted or trisubstituted by halogen, halogenoalkyl, halogenoalkoxy, alkyl, alkoxy, alkylthio, alkylsulphonyl, cyano, nitro or alkoxycarbonyl, the substitutents being identical or different, or represents pentafluorophenyl or represents a straight-chain, branched or cyclic alkyl which is unsubstituted or substituted by halogen, aryl, aryloxy, cyano, alkoxycarbonyl, alkoxy, alkylthio or trifluoromethyl, and PA1 X represents an --O--, --A--B-- or --B--A-- group, where PA2 A denotes --O--, ##STR2## B denotes --O--; ##STR3## where R.sup.1 does not represent a pyridyl radical when X represents an --O-- group, and salts thereof are prepared by reacting appropriate amines with sulphonyl halides. The substituted phe…