Indenyl hydroxamic acids and hydroxy ureas as inhibitors of 5-lipoxygenase
US5093356A · kind A · utility
33Cited by
12References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 16, 1990 |
| Grant date | Mar 3, 1992 |
| Priority date | — |
| Expiry date | Jan 16, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D333/20
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds having the formula I: ##STR1## are inhibitors of the 5-lipoxygenase enzyme. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating diarrhea, hypertension, angina, platelet aggregation, cerebral spasm, premature labor, spontaneous abortion, dysmenorrhea, and migraine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.