Retinoid compounds
US5094783A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 29, 1990 |
| Grant date | Mar 10, 1992 |
| Priority date | — |
| Expiry date | Jun 29, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/16
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Retinoid compounds with bioactive properties and their synthesis are described. The compounds are useful as chemopreventive or cancer-treating agents and dermatological agents. The novel retinoids are members of either of the two general structures: ##STR1## wherein X is CO.sub.2 H or CH.sub.2 OH; and in formula (I), R.sub.1 and R.sub.2 are each hydrogen, a C.sub.1-4 alkyl, a C.sub.1-4 alkoxy, or R.sub.1 and R.sub.2 taken together form a 5- to 7-membered cycloalkyl or cycloalkenyl ring; and in formula (II), R.sub.1 and R.sub.2 are each hydrogen, a C.sub.1-4 alkyl, a C.sub.1-4 alkenyl or a C.sub.1-4 alkoxy, or R.sub.2 and R.sub.3 taken together form a 5- to 7-membered cycloalkyl or cycloalkenyl with R.sub.1 and R.sub.4 being a hydrogen atom, a C.sub.1-4 alkyl, a C.sub.1-4 alkenyl or a C.sub.1-4 alkoxy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.