Oligopeptide antibiotics

US5095139A · kind A · utility

Assignee

• Ciba-Geigy · US

Inventors

• Wolfgang Loeffler · Basel, CH
• Martin Kugler · Leichlingen, DE
• Gunther Jung · Tübingen, DE
• Armin Kern · Wuppertal, DE
• Claudius Rapp · Tübingen, DE

Key dates

• Filing date: Apr 26, 1990
• Grant date: Mar 10, 1992
• Expiry date: Apr 26, 2010

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Rhizocticines of the formula ##STR1## in which X represents hydrogen or a hydrophobic amino acid radical and Y represents a basic amino acid radical, the C2 atoms of the amino acid radicals having the L-configuration, and protected derivatives and salts thereof. The compounds are obtained from culture broths of Bacillus subtilis or synthetically and have especially fungicidal action.