Antibacterial polypeptides
US5096886A · kind A · utility
3Cited by
3References
22Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | May 31, 1990 |
| Grant date | Mar 17, 1992 |
| Priority date | — |
| Expiry date | May 31, 2010 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A polypeptide having bactericidal activity, particularly against gram-negative bacteria, has been isolated from pig intestine. The porcine cecropin has the amino acid sequence: H.sub.2 N-Ser-Trp-Leu-Ser-Lys-Thr-Ala-Lys-Lys-Leu-Glu-Asn-Ser-AlaLys-Lys-Arg-Ile-S er-Glu-Gly-Ile-Ala-Ile-Ala-Ile-Gln-Gly-Gly-Pro-Arg-COOh. Pharmaceutical compositions containing such poypeptides, or functional derivatives thereof, are useful in therapeutic and prophylactic methods for inhibiting bacterial growth.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.