Basic cleavage products of elaiophylin and elaiophylin derivatives and use thereof

US5096905A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Gerhard Kretzschmar · Eschborn, DE
• Peter Hammann · Kelkheim, DE
• Dieter Duwel
• Gerhard Wohner · Flörsheim, DE
• Rudiger Marquardt · Frankfurt am Main, DE
• Klaus Kuhlein · Kelkheim, DE

Key dates

• Filing date: Sep 14, 1989
• Grant date: Mar 17, 1992
• Expiry date: Sep 14, 2009

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D309/10
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to elaiophylin derivatives of the formulae (I), (I'), (III) and (III') ##STR1## in which the C.dbd.C double bonds in the 2,3 and 4,5 position may also be hydrogenated and in which R.sup.1, R.sup.2, R.sup.3, R.sup.4 and X have the meanings indicated. The invention furthermore relates to a process for the preparation of these elaiophylin derivatives, and the use thereof as pharmaceuticals, in particular as anthelmintic pharmaceuticals.