2-substituted-4-substituted-5-amino-2H-pyridazin-3-ones

US5097028A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Joachim Weissmuller · Monheim, DE
• Peter Babczinski · Wuppertal, DE
• Klaus Lurssen · Wittlich, DE
• Hans-Joachim Santel · Leverkusen, DE
• Robert R. Schmidt · Cologne, DE
• Birgit Krauskopf · Bensberg, DE

Key dates

• Filing date: Jul 13, 1990
• Grant date: Mar 17, 1992
• Expiry date: Jul 13, 2010

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D237/22
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to new 2H-pyridazinone derivatives of the general formula (I) ##STR1## in which R.sup.1 represent alkyl, alkoxyalkyl, alkylthioalkyl, aminoalkyl, alkylaminoalkyl, dialkylaminoalkyl, hydroxyalkyl, halogenoalkyl, cyanoalkyl, alkenyl, halogenalkenyl or alkoxycarbonylalkyl, or represents in each case optionally substituted cycloalkyl, cycloalkylalkyl, phenyl or phenylalkyl, PA0 R.sup.2 represents alkyl, or represents in each case optionally substituted phenyl, phenoxy or phenylalkyl, PA0 R.sup.3 represents hydrogen, or represents in each case optionally substituted alkyl, cycloalkyl or alkylcarbonyl, and PA0 R.sup.4 represents hydrogen, hydroxyl, amino, aminocarbonyl (carbamoyl), or represents alkoxy, alkylamino or dialkylamino, or represents in each case optionally substituted alkyl, cycloalkyl, alkylaminocarbonyl, dialkylaminocarbonyl, alkylcarbonyloxy, alkylcarbonylamino, alkylcarbonylalkylamino, bis-(alkylcarbonyl)-amino, alkoxycarbonyl, alkoxycarbonylcarbonyl, formyl or alkylcarbonyl, have been found.