Process for preparing optically active 2-arylpropionic acids
US5097064A · kind A · utility
2Cited by
7References
14Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Aug 30, 1990 |
| Grant date | Mar 17, 1992 |
| Priority date | — |
| Expiry date | Aug 30, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C51/36
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention relates to a process for preparing an optically active 2-arylpropionic acid of general formula (I), by the hydrogenation, in a heterogeneous aqueous-organic medium, of a 2-arylacrylic acid of general formula (II) in the presence of a catalyst consisting of a rhodium derivative and a water-soluble chiral ligand. In the general formulae (I) and (II), Ar represents an optionally substituted monocyclic or polycyclic aromatic radical or an optionally substituted aromatic heterocyclic radical: ##STR1##
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.