Imidazole compounds and their use as transglutaminase inhibitors
US5098707A · kind A · utility
24Cited by
2References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 29, 1991 |
| Grant date | Mar 24, 1992 |
| Priority date | — |
| Expiry date | Apr 29, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D401/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compositions useful for thrombolytic therapy comprising a plasminogen activator such as tPA or streptokinase together with an imidazolium salt having the formula ##STR1## in a pharmaceutically acceptable carrier and methods for inhibiting hard clot formation or supplementing fibrinolytic therapy are described. The imidazolium salt also may be used with a platelet aggregation inhibitor or anticoagulant.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.