Patent · US Expired

Spiro-dihydroisoindole compounds

US5098925A · kind A · utility

2Cited by
2References
21Claims
0Family size

Assignee

Inventor

Key dates

Filing dateFeb 5, 1991
Grant dateMar 24, 1992
Priority date
Expiry dateFeb 5, 2011

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D209/96
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to spiroisoindolines that are antagonists at the phencyclidine receptor of the N-methyl-D-aspartate receptor complex and which are useful when such antagonism is desired such as in the treatment of neurological disorders. The invention further provides processes for preparing the spiroisoindolines, intermediates useful for their synthesis, pharmaceutical compositions containing them, and methods for their use.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.