Patent · US Expired

Chroman-2-carboxamide conjugates and their use for treatment of reperfusion injury

US5099012A · kind A · utility

20Cited by
2References
28Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 11, 1990
Grant dateMar 24, 1992
Priority date
Expiry dateDec 11, 2010

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC08B37/0021
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Conjugates of 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid with p-aminophenylsaccharides, with aminoalkyl-derivatized dextrans and with polylysines and polyornithines are prepared by condensation using diimides. Methods and compositions for the use of such conjugates to protect mammals from reperfusion injury are also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.