Process for the preparation of pure, unsymmetrically disubstituted ureas

US5099021A · kind A · utility

Assignee

• Agrolinz Agrarchemikalien Gesellschaft m.b.H. · AT

Inventors

• Rudolf H. Worther · Linz, AT
• Horst Korntner · Linz, AT
• Egmont Auer · Linz, AT
• Kurt Thonhofer · Linz, AT

Key dates

• Filing date: Oct 30, 1990
• Grant date: Mar 24, 1992
• Expiry date: Oct 30, 2010

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C273/1854
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Process for the preparation of pure, unsymmetrically disubstituted ureas of the general formula ##STR1## in which R denotes a phenyl radical which is unsubstituted, or monosubstituted or polysubstituted by halogen atoms or alkyl, alkoxy, aryloxy or trifluoromethyl groups, an oxazolyl, isoxazolyl, thiazolyl, isothiazolyl, benzoxazolyl or benzothiazolyl radical which is unsubstituted, or monosubstituted or polysubstituted by halogen atoms or alkyl, alkoxy or trifluoromethyl groups and R.sub.1 and R.sub.2 independently of one another denote a hydrogen atom or an alkyl group, where R.sub.1 and R.sub.2 are not simultaneously hydrogen or R.sub.1 and R.sub.2 together denote a butylene or pentylene group, by reaction of an N-alkyl- or N,N-dialkylurea with an unsubstituted or substituted arylamine or a heterocyclic amine in the presence of that amine which is already present in the starting material, the respective N-alkyl- or N,N-dialkylurea.