Chiral phosphorus compounds, a process for their manufacture and their application to the catalysis of enantioselective synthesis reactions
US5099077A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 11, 1989 |
| Grant date | Mar 24, 1992 |
| Priority date | — |
| Expiry date | Oct 11, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/16
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A method of using a chiral phosphorus-containing ligands comprising at least one amine radical and at least one dihydrocarbylphosphioxy radical of the formula W=OP (R).sub.2 ; from the group consisting of: those of the formula ##STR1## those of the formula ##STR2## those of the formula ##STR3## those of the formula ##STR4## in a hydrogenation reaction for the synthesis of optically active organic compounds comprising reacting at least one organic compound that does not possess a center of asymmetry with (A), on the one hand, at least one transition metal complex of the formula MZq in which M is a metal in group VIII of the Periodic Classification, q is the coordination number of the metal M, and Z is an atom or molecule capable of complexing the metal M and (B), on the other hand, at least one ligand L.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.