Process for preparing lipid microparticles
US5100591A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 14, 1990 |
| Grant date | Mar 31, 1992 |
| Priority date | — |
| Expiry date | Sep 14, 2010 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/7048
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a process for preparing lipid microparticles of microcrystalline appearance, of a water-insoluble substance possessing an affinity for phospholipids and of at least one phospholipid, the microparticles being stable in suspension in an aqueous solution, characterized in that: PA0 a) the said substance and the said phospholipid or phospholipids are dissolved in a common organic solvent for the said substance and for the said phospholipid or phospholipids, PA0 b) the solution of said substance and of the said phospholipid or phospholipids is mixed with an aqueous solution in an amount such that an insolubilization takes place in the form of a precipitate, and PA0 c) the organic solution is removed to recover an aqueous solution containing the microparticles in the form of microsuspensions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.