Process for the preparation of L-amino acids and amino acid amides

US5100782A · kind A · utility

Assignee

• SCHERING CORPORATION · US

Inventors

• Uwe Klages · Berlin, DE
• Alfred Weber · Wien, AT

Key dates

• Filing date: Jan 5, 1990
• Grant date: Mar 31, 1992
• Expiry date: Jan 5, 2010

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12P13/02
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The disclosure relates to a process for the preparation of L-amino acids of general Formula I ##STR1## wherein A means the residue of an amino acid molecule, from D,L-aminonitriles of general Formula II ##STR2## wherein A has the meaning given above, characterized by fermenting the .alpha.-aminonitriles with a culture of Actinetobacter calcoaceticus DSM 3875 and reacting the thus-obtained D,L-amino acid amides of general Formula III ##STR3## wherein A has the meaning given above, with a culture of a microorganism containing amino acid amide racemases and L-amino acid amide amidases.