Dihydropyridine vasodilator agents
US5100892A · kind A · utility
3Cited by
16References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 13, 1990 |
| Grant date | Mar 31, 1992 |
| Priority date | — |
| Expiry date | Nov 13, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D401/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of the following formula (I): ##STR1## where R.sup.1 and R.sup.2 are alkyl or cycloalkyl, which may be substituted, R.sup.4 is aryl such as phenyl which may be substituted, L is a direct bond or an oxygen containing linking group, R is a hydrogen, alkyloxy, alkyl, halogen or haloalkyl and Het is a pyridinyl or pyridazinyl group. The compounds can be used antihypertensives or myocardial relaxants. Also part of the invention are pharmaceutical compositions, intermediates and methods of synthesis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.