Antibodies for providing protection against P. vivax malaria infection
US5101017A · kind A · utility
7Cited by
1References
3Claims
0Family size
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Key dates
| Filing date | Apr 6, 1987 |
| Grant date | Mar 31, 1992 |
| Priority date | — |
| Expiry date | Apr 6, 2007 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/809
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A monoclonal antibody which identifies the human blood group Duffy (ab) is provided. Such monoclonal antibody blocks the penetration of P. vivax malaria parasite into human red blood cells by virtue of effective blocking of the target molecule of the P. vivax malaria parasite. Such monoclonal antibody has a combining site having the same stereochemistry as the ligand site on P. vivax, and elicits anti-idiotypic antibodies that react with the parasite.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.