Preparation of heteroaryloxyacetamides

US5101034A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Thomas Schmidt · Neustadt, DE
• Hans-Joachim Diehr · Wuppertal, DE

Key dates

• Filing date: Mar 7, 1991
• Grant date: Mar 31, 1992
• Expiry date: Mar 7, 2011

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process for the preparation of a heteroaryloxyacetamide of the formula ##STR1## in which R is a 5 membered heterocycle which may be benzo-fused, and PA0 R.sup.1 and R.sup.2 each independently is hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl or cycloalkenyl, halogenoalkyl, alkoxyalkyl, alkoxy, aralkyl or aryl, or PA0 R.sup.1 and R.sup.2, together with the nitrogen atom to which they are bonded, form a heterocycle, which comprises reacting a sulphonylated heteroaromatic of the formula EQU R--SO.sub.2 --R' in which PA0 R' is lower alkyl or benzyl, with an .alpha.-oxyacetamide of the formula ##STR2## in which R" is hydrogen or acyl, in the presence of an inorganic base as an acid acceptor and of solvent as a diluent at a temperature of about -50.degree. C. to +150.degree. C. The products are known herbicides.