Patent · US Expired

.beta.-D-phenylthioxylosides, their method of preparation and their use as therapeutic agents

US5101048A · kind A · utility

7Cited by
3References
6Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 18, 1989
Grant dateMar 31, 1992
Priority date
Expiry dateOct 18, 2009

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07H15/203
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention relates, by way of novel industrial products, to the .beta.-D-phenylthioxyloside compounds of the formula ##STR1## in which: X represents a sulfur atom or an oxygen atom; PA0 R.sub.1, R.sub.2 and R.sub.3, which are identical or different, each represent a hydrogen atom, a nitro group, a cyano group, a group --CO--R (in which R represents a C.sub.1 -C.sub.4 alkyl group or a trifluoromethyl group), an amino group, an acetamido group (NHCOCH.sub.3), a C.sub.1 -C.sub.4 alkoxy group, a trifluoromethyl group or a phenyl group substituted by one or more cyano, nitro or trifluoromethyl groups, it being possible for R.sub.1 and R.sub.2, taken together, to form, with the phenyl group to which they are bonded, a .beta.-naphthalenyl group which is unsubstituted or substituted by one or more cyano, nitro or trifluoromethyl groups; and PA0 Y represents the hydrogen atom or an aliphatic acyl group. These compounds are useful as therapeutic agents, especially as venous antithrombotics.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.