Method for culturing animal cells
US5102790A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 19, 1988 |
| Grant date | Apr 7, 1992 |
| Priority date | — |
| Expiry date | Dec 19, 2008 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12M25/16
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method of using an apparatus for the in vitro cultrue of animal cells to recover secreted proteins of interest therefrom, affording the capability of being readily and predictably scaled up or down to desired protein productin rates, comprised of a housed arrangement of culture subunits containing a packed bed of carrier particles, each subunit being fed in parallel from a common culture medium source, and the spent culture fluid from each subunit being directed to a common spent fluid conduit within the housed arrangement. Scale-up or scale-down is effected by addition or subtraction of culture subunits and/or by increase or decrease in carrier particle volume within a subunit while maintaining substantially constant packed bed height.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.