Substituted piperidine compounds and their use
US5102894A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 3, 1990 |
| Grant date | Apr 7, 1992 |
| Priority date | — |
| Expiry date | Dec 3, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D409/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel piperidine compounds having the formula I ##STR1## wherein R.sup.3 is 3,4-methylenedioxyphenyl, phenyl, naphthyl, which are optionally substituted with one or two halogen, amino, C.sub.1-6 -alkyl mono-or disubstituted amino group, C.sub.1-6 -alkoxy, cyano, mono-, di- or trihalogenated C.sub.1-6 -alkyl, C.sub.2-6 -alkenyl, C.sub.1-6 alkyl, C.sub.3-5 -alkylene, trifluoromethoxy, or trifluoromethyl groups, PA0 R.sup.1 is hydrogen, straight or branched C.sub.1-8 -alkyl, C.sub.1-8 -alkoxy-C.sub.1-8 -alkyl, C.sub.3-8 -cycloalkyl, C.sub.2-6 -alkenyl, C.sub.4-8 -cycloalkylalkyl, C.sub.2-6 -alkynyl PA0 Z is hydrogen, straight or branched C.sub.1-8 -alkyl, PA0 Y is O or S PA0 X is O, S or NR, wherein R is hydrogen or C.sub.1-4 -alkyl or a salt thereof with a pharmaceutically acceptable acid. The novel compounds are useful in the treatment of anoxia, traumatic injury, ischemia, migraine and epilepsy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.