Test carrier and method for the analytical determination of components of body fluids

US5104811A · kind A · utility

Assignee

• Boehringer Mannheim GmbH · DE

Inventors

• Dieter Berger · Viernheim, DE
• Wolfgang-Reinhold Knappe · Ludwigshafen, DE
• Robert D. Lorenz · Madison, US
• Henry Grage · Johns Creek, US
• Mark T. Skarstedt · Elkhart, US
• Bernward Sojka · Viernheim, DE
• Manfred Bleisteiner · Mannheim, DE

Key dates

• Filing date: Dec 18, 1987
• Grant date: Apr 14, 1992
• Expiry date: Dec 18, 2007

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S436/81
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

On a carrier layer there are arranged several test layers which are at least partly in fluid contact with one another, enabling liquid exchange. On the carrier layer are arranged an application zone, a detection zone for the production of a detectable signal characteristic of the analytical determination, which contains at least one said test layer which is a reaction layer, and an absorption zone with a test layer which is an absorptive layer of an absorbent material, wherein the reaction layer and absorption zone are positioned next to each other. Between the application and the absorption zone is a capillary-active transport path on the carrier layer which connects the application zone and the absorption zone. The reaction layer is arranged parallel to the transport path between the application zone and the absorption zone in such a manner that it is in liquid contact with a liquid transported in the transport path. The absorption zone therefore absorbs excess liquid and permits dosing the reaction layer with a reproducible amount of sample.