Patent · US Expired

Thiazolidine derivatives, their preparation and use

US5104888A · kind A · utility

35Cited by
1References
37Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 25, 1990
Grant dateApr 14, 1992
Priority date
Expiry dateJul 25, 2010

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D495/10
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Compounds of formula (I): ##STR1## (in which R.sup.1 -R.sup.7 are hydrogen or various organic groups, n is 1-10, Ar is an aromatic group, U is CH.sub.2 or a carbon atom doubly bonded to either one of its adjacent carbons, and W is >CH.sub.2, >C.dbd.O, >CHOH, >C.dbd.NOH or various derivatives thereof) have the ability to lower the levels of blood lipid peroxides and blood sugars and to inhibit the activity of aldose reductase; they may be used therapeutically for these purposes.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.