Thiazolidine derivatives, their preparation and use
US5104888A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 25, 1990 |
| Grant date | Apr 14, 1992 |
| Priority date | — |
| Expiry date | Jul 25, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D495/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of formula (I): ##STR1## (in which R.sup.1 -R.sup.7 are hydrogen or various organic groups, n is 1-10, Ar is an aromatic group, U is CH.sub.2 or a carbon atom doubly bonded to either one of its adjacent carbons, and W is >CH.sub.2, >C.dbd.O, >CHOH, >C.dbd.NOH or various derivatives thereof) have the ability to lower the levels of blood lipid peroxides and blood sugars and to inhibit the activity of aldose reductase; they may be used therapeutically for these purposes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.