Patent · US Expired

Platinum(II) complexes, their preparation and use as anti-tumor agents

US5104895A · kind A · utility

33Cited by
16References
4Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 5, 1990
Grant dateApr 14, 1992
Priority date
Expiry dateNov 5, 2010

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P35/00
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Compounds of formula I ##STR1## wherein R.sub.1 and R.sub.2, that can be the same or different, are hydrogen, alkyl, aryl, aralkyl groups or, if taken together, cycloalkyl groups; PA0 A is a carbon atom, a residue of 2,3-dioxybutandioic-2,4-dioxyphtalic acid or disubstituted malonic acid derivatives; PA0 n.sub.1 and n.sub.2 are selected in such a manner that the result of their addition is from 2 to 40; PA0 T.sub.1 and T.sub.2 that can be the same or different, are hydrogen, alkyl, benzyl, phenyl, acyl or cycloalkyl or a residue of formulae ##STR2## Compounds I are useful as anti-tumor agents in human therapy.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.