Patent · US Expired

Neurological therapy devices

US5106627A · kind A · utility

196Cited by
9References
33Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 14, 1990
Grant dateApr 21, 1992
Priority date
Expiry dateNov 14, 2010

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2533/30
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Neurological therapy devices are disclosed for the local and controlled delivery of a neurotransmitter to the brain of a subject suffering from neurotransmitter deficiency or dysfunction. In one embodiment the device includes a biocompatible, implantable, and retrievable polymeric insert including a source of neurotransmitter embedded therein. In another embodiment, the device includes a retrievable source of neurotransmitter including at least one neurotransmitter-secreting cell encapsulated within a semipermeable membrane allowing the diffusion therethrough of the neurotransmitter, and further includes a source of growth factor in close proximity to the neurotransmitter-secreting cells.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.