2-hydrocarbyl-3,6-dichloropyridines and their preparation
US5106984A · kind A · utility
13Cited by
11References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 24, 1987 |
| Grant date | Apr 21, 1992 |
| Priority date | — |
| Expiry date | Feb 24, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D213/61
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
2-Hydrocarbyl-3,6-dichloropyridines are prepared from dichloromethyl hydrocarbyl ketones and acrylonitrile in a two-step process involving an addition reaction under basic conditions to form intermediate 1,1-dichloro-3-cyanopropyl hydrocarbyl ketones and a subsequent cyclization reaction in the presence of hydrogen chloride. Thus, 3,6-dichloro-2-methylpyridine is prepared from 1,1-dichloro-2-propanone and acrylonitrile by the formation and further reaction of 4,4-dichloro-5-oxo-hexanenitrile. The intermediates and products are novel compounds useful in the preparation of herbicides and nitrification inhibitors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.