Bioadhesives for cell and tissue adhesion
US5108923A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 3, 1987 |
| Grant date | Apr 28, 1992 |
| Priority date | — |
| Expiry date | Apr 3, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2533/50
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A cell culturing system, methods for the preparation thereof, and methods for affixing other biologically active moieties to a substrate are provided. Said cell culturing system comprises: a substrate; a coating thereon of a sterile formulation comprising polyphenolic protein containing from about 35 to 100% by weight pure bioadhesive polyphenolic protein having the repeating decapeptide unit: ##STR1## wherein N is a whole number ranging from about 10 to about 100, wherein each X is independently selected from the group consisting of hydroxyl and hydrogen, and wherein each R is independently selected from the group consisting of hydrogen and methyl; viable cells affixed to said coated substrate; and a nutritive medium contacting said cells, whereby said cells perform normal metabolic cell functions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.