Use of a solution of alpha-chymotrypsin
US5110590A · kind A · utility
Inventor
Key dates
| Filing date | Feb 6, 1990 |
| Grant date | May 5, 1992 |
| Priority date | — |
| Expiry date | Feb 6, 2010 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Preparation and use of a composition of alpha-chymotrypsin in either a physiologically suitable solution or suspension medium, in a dilution of 1:10,000 to 1:30,000, corresponding to a ratio of amounts of 1 milligram of alpha-chymotrypsin to 10 to 30 milliliters of the solution medium, or in a dispersion, by volume, of preferably 1:15,000 to 1:20,000 of the alpha-chymotrypsin to the suspension medium, for the treatment and cleaning of the posterior lens capsule left behind in an extracapsular cataract operation. The composition, in its final application solution or dispersion form contains an amount of a viscoelastic substance adapted for intraocular or intraorbital surgical operations and suitable for combatting or preventing unwanted further dilution of the alpha-chymotrypsin, regardless of the amount of fluids either present or subsequently collected in the eye during the posterior lens cleaning operation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.