Process for the preparation of 3-(lpyroglutamyl)-L-thiazolidine-4-carboxylic acid derivatives
US5110936A · kind A · utility
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Key dates
| Filing date | Oct 9, 1990 |
| Grant date | May 5, 1992 |
| Priority date | — |
| Expiry date | Oct 9, 2010 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
3-(L-pyroglutamyl)-L-thiazolidine-4-carboxylic acid and derivatives thereof are prepared by condensing L-pyroglutamic acid or its substitution products, either in the presence of dicyclohexylcarbodiimmide or the like, or by condensation of active derivatives of L-pyroglutamic acid with 4-thiazolidine-carboxylic acid derivatives.
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