Bone allograft material and method
US5112354A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Nov 16, 1989 |
| Grant date | May 12, 1992 |
| Priority date | — |
| Expiry date | Nov 16, 2009 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61F2250/0098
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A textured, demineralized, and unitary mammalian bone section for providing a rigid, foraminous, collagen scaffold for allogenic skeletal reconstruction. The allograft is prepared by treating a section of cadaver bone to remove all soft tissue, then texturing the bone surface to produce a pattern of holes of selected size, density, and depth, and finally demineralizing the bone section to leave a rigid, insoluble collagen scaffold suitable for osteoinduction upon implantation. All such steps are performed with minimal denaturing of the extracellular matrix proteins which remain bound to the collagen scaffold and which are necessary to complete the process of new bone formation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.