Method for analytically utilizing microfabricated sensors during wet-up
US5112455A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 20, 1990 |
| Grant date | May 12, 1992 |
| Priority date | — |
| Expiry date | Jul 20, 2010 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N27/3274
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method of determining the concentration of a preselected analyte species present in a sample fluid is disclosed, which method comprises: (a) providing an external computational means, a reference electrode and at least one substantially dry-stored sensor capable of exhibiting a response to changes in the concentration of a preselected analyte species before the sensor attains full equilibrated wet-up; (b) establishing electrical contact between the sensor, reference electrode and external computational means; (c) contacting the sensor and reference electrode with a calibrant fluid; (d) performing a first signal measurement in a first time window in the presence of the calibrant fluid; (e) displacing the calibrant fluid after performing the first signal measurement; (f) contacting the sensor and reference electrode with a sample fluid; (g) performing a second signal measurement in a second time window in the presence of the sample fluid; and (h) relating the first and second signal measurements to determine the concentration of the preselected analyte species in the sample fluid before said sensor attains full equilibrated wet-up. Alternative methods are disclosed further for coll…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.