Sustained release pharmaceutical composition of diltiazem
US5112621A · kind A · utility
58Cited by
4References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 26, 1990 |
| Grant date | May 12, 1992 |
| Priority date | — |
| Expiry date | Jul 26, 2010 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/55
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A sustained-release pharmaceutical composition which comprises microparticles comprising an active principle, said microparticles being coated with a coating mixture comprising ethyl cellulose and an acrylic resin which is a polymerizate of acrylic and methacrylic ester, having a molecular weight of at least 100,000 and comprising units of formula: ##STR1## wherein: R.sub.1 is hydrogen or methyl, PA1 R.sub.2 is methyl or ethyl, PA1 R.sub.3 is methyl; and PA1 R.sub.4 is --CH.sub.2 --CH.sub.2 N(CH.sub.3).sub.3 Cl the resin containing 5% of trimethylammonium methacrylate chloride units by weight.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.