Octalactone-containing composition, fermentation process for producing same and organoleptic uses thereof
US5112803A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 21, 1991 |
| Grant date | May 12, 1992 |
| Priority date | — |
| Expiry date | Jun 21, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P17/04
- WIPO fieldBasic materials chemistry
- WIPO sectorChemistry
Abstract
Described is a process for the preparation of compositions of matter containing octalactones defined according to the structure: ##STR1## which includes the stereoisomers having the structures: ##STR2## by means of the sequential steps of (i) fermentation of caprylic acid or the ethyl ester of caprylic acid defined according to the generic structure: ##STR3## wherein R is hydrogen or ethyl using a microorganism selected from the group consisting of: PA0 Mortierella isabellina, ATCC 44583; PA0 Mortierella isabellina, ATCC 38063; PA0 Syncephalastrum racemosum, NRRL A-5889; PA0 Mortierella isabellina, IFO 7884; PA0 Mortierella ramanniana var. angulispora, IFO 8187; PA0 Mortierella isabellina, CBS 221.29; and PA0 Mortierella isabellina, IFO 7873 whereby gamma hydroxy octanoic acid or ester thereof defined according to the structure: ##STR4## is formed; and (ii) lactonization of the resulting gamma hydroxy octanoic acid by means of simultaneous acidification and heating according to the reaction sequence:
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.